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The Pfitzner–Moffatt oxidation, sometimes referred to as simply the Moffatt oxidation, is a chemical reaction which describes the oxidation of primary and secondary alcohols by dimethyl sulfoxide (DMSO) activated with a carbodiimide, such as dicyclohexylcarbodiimide (DCC). The resulting alkoxysulfonium ylide rearranges to generate aldehydes and ketones, respectively.〔J. G. Moffatt, “Sulfoxide-Carbodiimide and Related Oxidations” in ''Oxidation'' vol. 2, R. L. Augustine, D. J. Trecker, Eds. (Dekker, New York, 1971) pp 1–64.〕 : This reaction has been largely abandoned for the Swern oxidation, which gives higher yields with fewer side products. The Moffatt oxidation yields urea by-products that are often difficult to remove. Several reviews have been published.〔Tidwell, T. T. ''Org. React.'' 1990, ''39'', 297–572. (Review)〕〔Lee, T. V. ''Comp. Org. Syn.'' 1991, ''7'', 291–303. (Review)〕 Reaction mechanism is as follows. : ==See also== * Corey–Kim oxidation * Swern oxidation 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Pfitzner–Moffatt oxidation」の詳細全文を読む スポンサード リンク
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